AFC South
| Round | Kickoff | Away | Home | Venue | Result |
|---|---|---|---|---|---|
| Regular season (Week 1) |
Sunday 09/13/2026 1:00 PM EDT |
New York Jets | Tennessee Titans | Nissan Stadium | 23 : 10 |
| Regular season (Week 2) |
Sunday 09/20/2026 1:00 PM EDT |
Philadelphia Eagles | Tennessee Titans | Nissan Stadium | 24 : 20 |
| Regular season (Week 3) |
Sunday 09/27/2026 1:00 PM EDT |
Tennessee Titans | New York Giants | MetLife Stadium | 7 : 12 |
| Regular season (Week 4) |
Sunday 10/04/2026 1:00 PM EDT |
Tennessee Titans | Baltimore Ravens | M&T Bank Stadium | 18 : 24 |
| Regular season (Week 5) |
Sunday 10/11/2026 1:00 PM EDT |
Houston Texans | Tennessee Titans | Nissan Stadium | 26 : 3 |
| Regular season (Week 6) |
Sunday 10/18/2026 1:00 PM EDT |
Tennessee Titans | Indianapolis Colts | Lucas Oil Stadium | 26 : 20 |
| Regular season (Week 7) |
Sunday 10/25/2026 1:00 PM EDT |
Cleveland Browns | Tennessee Titans | Nissan Stadium | 27 : 24 |
| Regular season (Week 8) |
Sunday 11/01/2026 1:00 PM EST |
Tennessee Titans | Cincinnati Bengals | Paycor Stadium | |
| Regular season (Week 10) |
Sunday 11/15/2026 1:00 PM EST |
Jacksonville Jaguars | Tennessee Titans | Nissan Stadium | |
| Regular season (Week 11) |
Sunday 11/22/2026 1:00 PM EST |
Tennessee Titans | Dallas Cowboys | AT&T Stadium | |
| Regular season (Week 12) |
Sunday 11/29/2026 4:05 PM EST |
Tennessee Titans | Jacksonville Jaguars | EverBank Stadium | |
| Regular season (Week 13) |
Sunday 12/06/2026 1:00 PM EST |
Washington Commanders | Tennessee Titans | Nissan Stadium | |
| Regular season (Week 14) |
Sunday 12/13/2026 1:00 PM EST |
Tennessee Titans | Detroit Lions | Ford Field | |
| Regular season (Week 15) |
Sunday 12/20/2026 1:00 PM EST |
Indianapolis Colts | Tennessee Titans | Nissan Stadium | |
| Regular season (Week 16) |
Sunday 12/27/2026 4:05 PM EST |
Tennessee Titans | Las Vegas Raiders | Allegiant Stadium | |
| Regular season (Week 17) |
Sunday 01/03/2027 1:00 PM EST |
Pittsburgh Steelers | Tennessee Titans | Nissan Stadium | |
| Regular season (Week 18) |
Sunday 01/10/2027 1:00 PM EST |
Tennessee Titans | Houston Texans | Reliant Stadium |