AFC West
| Round | Kickoff | Away | Home | Venue | Result |
|---|---|---|---|---|---|
| Regular season (Week 1) |
Sunday 09/13/2026 4:25 PM EDT |
Arizona Cardinals | Los Angeles Chargers | SoFi Stadium | 26 : 14 |
| Regular season (Week 2) |
Sunday 09/20/2026 4:05 PM EDT |
Las Vegas Raiders | Los Angeles Chargers | SoFi Stadium | 26 : 14 |
| Regular season (Week 3) |
Sunday 09/27/2026 1:00 PM EDT |
Los Angeles Chargers | Buffalo Bills | Highmark Stadium | 16 : 24 |
| Regular season (Week 4) |
Sunday 10/04/2026 4:25 PM EDT |
Los Angeles Chargers | Seattle Seahawks | Lumen Field | 23 : 30 |
| Regular season (Week 5) |
Sunday 10/11/2026 4:05 PM EDT |
Denver Broncos | Los Angeles Chargers | SoFi Stadium | 23 : 17 |
| Regular season (Week 6) |
Sunday 10/18/2026 4:25 PM EDT |
Los Angeles Chargers | Kansas City Chiefs | GEHA Field at Arrowhead Stadium | 6 : 22 |
| Regular season (Week 8) |
Sunday 11/01/2026 4:05 PM EST |
Los Angeles Chargers | Los Angeles Rams | SoFi Stadium | |
| Regular season (Week 9) |
Sunday 11/08/2026 4:05 PM EST |
Houston Texans | Los Angeles Chargers | SoFi Stadium | |
| Regular season (Week 10) |
Monday 11/16/2026 8:15 PM EST |
Los Angeles Chargers | Baltimore Ravens | M&T Bank Stadium | |
| Regular season (Week 11) |
Sunday 11/22/2026 4:05 PM EST |
New York Jets | Los Angeles Chargers | SoFi Stadium | |
| Regular season (Week 12) |
Sunday 11/29/2026 8:20 PM EST |
New England Patriots | Los Angeles Chargers | SoFi Stadium | |
| Regular season (Week 13) |
Sunday 12/06/2026 1:00 PM EST |
Los Angeles Chargers | Tampa Bay Buccaneers | Raymond James Stadium | |
| Regular season (Week 14) |
Sunday 12/13/2026 4:05 PM EST |
Los Angeles Chargers | Las Vegas Raiders | Allegiant Stadium | |
| Regular season (Week 15) |
Thursday 12/17/2026 8:15 PM EST |
San Francisco 49ers | Los Angeles Chargers | SoFi Stadium | |
| Regular season (Week 16) |
Sunday 12/27/2026 1:00 PM EST |
Los Angeles Chargers | Miami Dolphins | Hard Rock Stadium | |
| Regular season (Week 17) |
Sunday 01/03/2027 1:00 PM EST |
Kansas City Chiefs | Los Angeles Chargers | SoFi Stadium | |
| Regular season (Week 18) |
Sunday 01/10/2027 1:00 PM EST |
Los Angeles Chargers | Denver Broncos | Empower Field at Mile High |