AFC North
| Round | Kickoff | Away | Home | Venue | Result |
|---|---|---|---|---|---|
| Regular season (Week 1) | 09/13/2026 01:00 PM EDT | Cleveland Browns | Jacksonville Jaguars | EverBank Stadium | |
| Regular season (Week 2) | 09/20/2026 01:00 PM EDT | Cleveland Browns | Tampa Bay Buccaneers | Raymond James Stadium | |
| Regular season (Week 3) | 09/27/2026 01:00 PM EDT | Carolina Panthers | Cleveland Browns | Huntington Bank Field | |
| Regular season (Week 4) | 10/01/2026 08:15 PM EDT | Pittsburgh Steelers | Cleveland Browns | Huntington Bank Field | |
| Regular season (Week 5) | 10/11/2026 01:00 PM EDT | Cleveland Browns | New York Jets | MetLife Stadium | |
| Regular season (Week 6) | 10/18/2026 01:00 PM EDT | Baltimore Ravens | Cleveland Browns | Huntington Bank Field | |
| Regular season (Week 7) | 10/25/2026 01:00 PM EDT | Cleveland Browns | Tennessee Titans | Nissan Stadium | |
| Regular season (Week 8) | 11/01/2026 01:00 PM EST | Cleveland Browns | Pittsburgh Steelers | Acrisure Stadium | |
| Regular season (Week 9) | 11/08/2026 01:00 PM EST | Cleveland Browns | New Orleans Saints | Caesars Superdome | |
| Regular season (Week 10) | 11/15/2026 01:00 PM EST | Houston Texans | Cleveland Browns | Huntington Bank Field | |
| Regular season (Week 12) | 11/29/2026 01:00 PM EST | Las Vegas Raiders | Cleveland Browns | Huntington Bank Field | |
| Regular season (Week 13) | 12/06/2026 01:00 PM EST | Cincinnati Bengals | Cleveland Browns | Huntington Bank Field | |
| Regular season (Week 14) | 12/13/2026 01:00 PM EST | Atlanta Falcons | Cleveland Browns | Huntington Bank Field | |
| Regular season (Week 15) | 12/20/2026 01:00 PM EST | Cleveland Browns | New York Giants | MetLife Stadium | |
| Regular season (Week 16) | 12/27/2026 01:00 PM EST | Cleveland Browns | Baltimore Ravens | M&T Bank Stadium | |
| Regular season (Week 17) | 01/03/2027 01:00 PM EST | Indianapolis Colts | Cleveland Browns | Huntington Bank Field | |
| Regular season (Week 18) | 01/10/2027 01:00 PM EST | Cleveland Browns | Cincinnati Bengals | Paycor Stadium |